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NEWS & USEFUL
INFORMATION
This page provides some of the latest
news and useful information related to hormone refractory prostate cancer. The newest items
appear at the top of the list.
3/1/13 - "The Changing Landscape in the Treatment of
Metastatic Castration-resistant Prostate Cancer"
This is another excellent article that describes the
recent advances in the treatment of HRPC/CRPC. It is by Joelle
El-Amm, MD, Jeanny B. Aragon-Ching, MD, FACP;
http://www.medscape.com/viewarticle/777315?src=nl_topic
2/5/13 - Cheat Sheet of Drug Names
All of the new drugs and treatments have had several
names during the course of their development. It's enough to drive a
person crazy. Here is a cheat sheet.
| Generic Name |
Brand Name |
Therapy Type - How Administered |
| Approved |
|
|
| Abiraterone |
Ztiga |
Hormonal Therapy - Oral |
| Cabazitaxel |
Jevtana |
Cytotoxic Therapy - Infusion |
| Denosumab |
Xgeva |
Bone-Directed Therapy - SC Injection |
| Docetaxel |
Taxotere |
Cytotoxic Therapy - Infusion |
| MDV3100 (Enzalutamide) |
Xtandi |
Hormonal Therapy - Oral |
| Sipuleucel-T |
Provenge |
Immunotherapy - Leukapheresis-like Infusion |
| |
|
|
| Not Yet Approved |
|
|
| Cabozantinib (XL184) |
Cometriq |
Targeted Therapy - Oral |
| Dasatinib |
Sprycel |
Bone-Directed Therapy - Oral |
| Prostvac |
|
Immunotherapy - Subcutaneous Injection |
| Radium-223 |
Alpharadin |
Bone-Directed Therapy - Infusion |
| Tasquinimod |
|
Immunotherapy - Oral |
| |
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2/5/13 - Overview of CRPC Management
and Novel Therapeutics An excellent summary of
the latest developments in treatments for HRPCa appeared in CA A Cancer
Journal for Clinicians in 2012:
Clinical Development of Novel Therapeutics for Castration-Resistant Prostate
Cancer
CA: A Cancer Journal for Clinicians
Matthew D. Galsky, Alexander C. Small, Che-kai Tsao, William K. Oh
DOI: 10.3322/caac.21141
http://onlinelibrary.wiley.com/doi/10.3322/caac.21141/full
Another excellent
overview of recent progress is a paper by Oliver Sartor, M.D.:
State-of-the-Art Management for the Patient with Castration-Resistant
Prostate Cancer in 2012, ASCO
http://www.asco.org/ASCOv2/Home/Education%20&%20Training/Educational%20Book/PDF%20Files/2012/zds00112000289.PDF
2/4/13 - Understanding your Bone
Scan Jan Manarite wrote a
very informative article on bone scans for the PRCI Insights Newsletter.
Click
here to read.
2/4/13 - Dealing with HRPCa
If you are dealing with HRPCa, this
book would be good to read and keep handy: Promoting Wellness - Beyond Hormone
Therapy - Options for Prostate Cancer Patients. Mark A. Moyad, M.D.,
M.P.H., Spry Publishing, an imprint of Ann Arbor Editions, LLC, 2011.
7/26/12 - This NEWS section was added by webmaster Howard Hansen at
the time when a whole bunch of new therapies for HRPCa were in the final
stages of testing. He proposed to use it to post promising results and
drug approvals as they happened. Sadly his own cancer was giving him
more trouble around this time and he succumbed to HRPCa in 2010.
We will use this page to provide news and information of interest to those
facing HRPCa.
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