Hormone-Refractory Prostate Cancer

or Castrate-Resistant Prostate Cancer

Understanding    Treating    Maintaining Quality of Life

What's New
What To Do First
Patient's Guide
E-mail Support Group
Proven Treatments
Being Revised
Potential Treatments
Being Revised
Managing Symptoms
Diagnostic Tests
Information Resources
Support HRPCA.org

If you have been to this web site previously, you can find links to most of the new additions at the  What's New pageSee also News for the latest announcements related to HRPCa.

www.hrpca.org All sites


Home Page of HRPCa.org

This web site was developed between 2001 and 2010 as a service to men, women, and their caregivers who are fighting hormone-refractory prostate cancer (HRPCa) also referred to as androgen-independent prostate cancer (AIPC) and more recently defined as castrate-resistant prostate cancer (CRPC).

This web site and the on-line support list are managed, written, and maintained by patients who are not medical professionals. We do not guarantee accuracy of information or success in the treatments discussed here. We urge you to involve your physician in the use of information gained here. See also About Us.

Who We Are

Almost all the writing on this web site is done by men fighting HRPCa or by women whose loved ones fought or are fighting prostate cancer. This web site is associated with the HRPCa e-mail support group (see e-mail support group).

INTRODUCTION to Hormone Refractory Prostate Cancer

Because there are differing opinions on what HRPCa means, we use a simple working definition.  Simply put, we define it as advanced prostate cancer that has resulted in 3 consecutive PSA rises while the individual is still on hormone therapy. The issue of the definition is discussed in detail in Definition of HRPCa.

A diagnosis of HRPCa is a serious development for the family fighting prostate cancer. It often comes accompanied by a grim prognosis that adds an emotional burden. All of the individuals working on this web site have been through this experience. Without exception, they have chosen to reject defeat and to fight this disease with their time, their ingenuity, their resources, and their computers.

What we have learned by sharing our experiences and our research efforts is that there are many choices open to the man with HRPCa. These choices can extend survival and maintain quality of life. First, there are lifestyle issues to consider. Next, there is a fairly clear set of therapies that should be considered by everyone. In addition, there are a number of clinical trials that can be considered. These options continue to grow in number as we watch the literature of allopathic medicine and alternative therapies.

This web site does not offer a cure, nor any guarantees of remission. It offers a process of managing this stage of the disease. It offers a forum for learning from other fighters and the opportunity for helping others in their fight. It offers the benefit of working with a committed team to find better solutions inside and outside traditional medicine.

Fighting HRPCa means learning as much as you can about your body, the disease, and the therapies. Start your education by reading the section What to do first.  If you are HRPCa, subscribe to the on-line support list. By these two steps, you can begin the process of coming to terms with HRPCa.

Every prostate cancer fighter needs a medical team. We believe in building our teams with doctors who respect the fact that we are in charge of our own treatment program. We respect those doctors for their expert input and compassionate care. We believe that the best way to use the information gained here is to share it with your doctors to arrive at the best decisions.


The information on this website was written between 2001 and 2010 by and for men with HRPCa (now called CRPC or mCRPC). The website content was developed for educational purposes only and does not replace or amend professional medical advice. Although proven and potential treatments have substantially changed since 2010, much of the website content is still relevant and helpful. See About Us for our policies and contact information. We are a 501(c)(3) not-for-profit public charity. 2001-2015 HRPCa Association, Inc.